TY - JOUR AU - Jacob, John Ryan AU - Chakravarti, Arnab AU - Palanichamy, Kamalakannan PY - 2019 TI - Nicotinamide N-methyltransferase epigenetic and metabolic rewiring promotes metastatic progression JF - Biotarget; Vol 3 (December 2019): Biotarget Y2 - 2019 KW - N2 - High-grade serous carcinoma (HGSC) is amongst the most deadly forms of cancer. Approximately 80% of patients with HGSC suffer recurrence following surgical resection and cytoreduction; a consequence of the widespread and inaccessible metastatic lesions throughout the abdominal cavity. HGSC progression and metastases co-evolves with the tumor microenvironment (TME), composing fibroblasts, mesenchymal stem cells, osteoblasts, and chondrocytes. UR - https://biotarget.amegroups.org/article/view/5210