%0 Journal Article
%T Quaking as a novel target of miR-200b to regulate tumor cell cycle progression mediated angiogenesis and metastasis
%A Nguyen, Tina H.
%A Alahari, Suresh K.
%J Biotarget
%D 2019
%B 2019
%9 
%! Quaking as a novel target of miR-200b to regulate tumor cell cycle progression mediated angiogenesis and metastasis
%K 
%X Tumor growth is mediated by several factors including metabolic function, intracellular signaling, evasion of apoptosis, tissue invasion and metastasis, and angiogenesis. Of these factors, angiogenesis is a crucial component due to its part in both delivering nutrients and providing a conduit for metastasis. Current anti-angiogenic therapies focus on tumor-derived VEGF signaling; however, these efforts are modest and prone to resistance by upregulation of other pro-angiogenic signaling (1,2). Due to incomplete knowledge of endothelial cell (EC) biology, other methods of impeding tumor angiogenesis are not available.
%U https://biotarget.amegroups.org/article/view/5038
%V 3
%P 
%@ 2522-669X